Abstract: Abstract： In order to investigate the mechanical properties of rock in cold region under cyclic loading, red sandstone that subjected to different freezing-thawing cycles is taken to carry out uniaxial compression test and uniaxial cyclic loading-unloading test. The results show that the peak strength and elastic modulus of rock is decreased gradually with the increase of the number of freeze-thaw cycles, while the peak strain and Poisson's ratio is increased gradually, and the failure of rock presents a tendency that transition from brittleness to ductility. The average modulus of cyclic loading and unloading is decreased rapidly with the increase of the number of freezing-thawing cycles, and the unit volumetric dissipation energy tends to increase with the increase of stress level, but the tendency is decreased with the increase of the number of freezing-thawing cycles.