Abstract: Taking the first section of the 21st floor of Junde Coal Mine as the background, the prevention and control of rock burst in the first section of the open-cut tunneling under the influence of coal pillar is studied by means of field survey, simulation analysis and vibration field-stress field monitoring. The results show that: (1) the concentrated stress of the upper coal pillar and the high stress formed by the lateral supporting pressure of the goaf of the coal pillar in this section are the main force sources of rock burst; (2) The calculation model of stress distribution in coal pillar affected area and lateral bearing pressure in goaf of coal pillar are established, which has an impact range of 138m and an impact risk of 52m; (3) According to the site conditions, formulate specific prevention and control plans for the early, middle and late stages of opening and cutting through tunneling, so as to realize the safety of opening and cutting through. The research results have a certain guiding significance for opening and cutting in similar situations.