Abstract：Aiming at the problem that the existing method of determining the hole spacing of gas extraction technology only relies on the simulation of gas transportation in the airspace area and field experience, lacks systematic and comprehensive analysis under the condition of multi-field coupling, and fails to fully consider other disaster-causing risk factors in addition to gas, this study takes the working face of 2-105 as the experimental area, and carries out the research by combining the simulation with the actual test method. Firstly, we simulated the gas transportation law in the mining area under different drilling distances to determine the basic interval of hole spacing; on this basis, we coupled the analysis of the temperature field, oxygen concentration field and wind speed field in the mining area to optimize the hole spacing; finally, we verified the simulation results through on-site measurements. The study shows that the hole spacing based on the gas field simulation is 25m, while the multi-field coupling analysis shows that increasing the spacing will lead to the enhancement of air leakage and the increase of oxygen concentration, which will lead to the expansion of spontaneous combustion zone and the migration of the high temperature zone, and therefore, the 20m dynamic extraction strategy is proposed. On-site measurements show that the gas concentration in the upper corner is lower than 0.8% in the interval of 15-35m between the drill holes and the working face, the maximum difference in oxygen concentration is 0.9%, and the maximum difference in temperature is 0.8K, which is smaller than the simulation results, and verifies the accuracy of the simulation. This study improves the application system of the gas extraction technology under multi-field coupling conditions, and provides a scientific and accurate technical basis and decision-making reference for its optimization and the prevention and control of coal mine gas and fire disasters.