Abstract: According to the difficult problem of stability control of mining roadway by repeated mining in steeply inclined coal seam, taking the typical mining roadway in steeply inclined coal seam as the engineering background, the in-situ monitoring, the numerical simulation and the similar simulation experiment are synthetically used to analyze the surrounding rock deformation and failure of roadway by repeated mining in steeply inclined coal seam. The results show that the deformation and failure of roadway surrounding rock is asymmetric under the effect of repeated mining, which is a complex time-space problem. Based on this, the support principle of "active support and strengthening control of key parts" is put forward, and the non-symmetrical coupling support method of strong bolt + long anchor rope + W steel belt + steel mesh is adopted to effectively control the roadway deformation and failure. The research results can provide reference for solving the roadway support problem of steeply inclined coal seam.