Abstract: With the increase of mining depth in Chensilou Coal Mine, the limestone water pressure and the probability of water inrush increase. After water inrush, the cost of drainage increases with the increase of mining depth. Water inrush from floor not only threatens mine safety, but also greatly reduces mine economic benefits. In particular, the limestone karst fissures in the upper section of Taiyuan Formation in the mining area of the south wing of the mine are developed, which have the characteristics of high water pressure, strong water yield and rich water supply, which pose a serious threat to the safety production of the mining face. In order to solve the problem of limestone water disaster prevention and control during the mining of coal seam in the deep mining area of the south wing of Chensilou Coal Mine, the 2506 working face (inner section) of the south wing of the mine took the lead in implementing the ground area treatment project of floor water disaster. Through the construction of ground boreholes, regional advance bedding exploration of limestone karst fissures, water diversion channels and water storage spaces, and high-pressure grouting plugging, The transformation of the aquifer into an equivalent aquifer has liberated the coal resources threatened by the high-pressure and strong aquifer. At present, the working face has been safely mined. The research results provide a reference example for Yongxia mining area and similar mines harmed by high confined water in the floor in China.