Abstract: Based on the development trend of domestic coal mine intelligent substation, this paper discusses the design and application of intelligent substation technology in coal mine power supply engineering, puts forward the intelligent design scheme and system architecture of 110kV Substation in Wucaiwan No. 1 coal mine, and analyzes the relevant technologies and equipment selection required for the construction of intelligent substation in simple terms. This paper focuses on the relevant technologies and design solutions of "process layer" of 110kV intelligent substation in Wucaiwan No. 1 coal mine, summarizes the "three-layer and two network" communication network structure of substation, and summarizes the problems existing in the design and application of 110kV intelligent substation in coal mine. This paper has a certain reference significance for the engineering design of coal mine intelligent substation.