Abstract: Based on practical engineering, the foundation design of factory buildings under complex karst geological conditions is studied and analyzed，Select different foundation types according to different geological conditions in site，According to the specification, the construction survey of rock-socketed piles is carried out one by one as the basis for the final hole of pile foundation，According to the on-site construction, various problems in the construction process are dealt with comprehensively considering various factors such as safety and reliability, engineering cost and construction convenience, so as to provide reference for similar projects.