Abstract: In order to systematically study the relationship between groundwater replenishment and discharge in Anxin Coalfield, and to master the law of groundwater seepage in Anxin Coalfield, a conceptual model of hydrogeology was established by means of numerical simulation, the stratigraphic structure and the boundary conditions of the model were generalized, and the evolution law of the seepage field of each aquifer in the upper part of the coal seam was analyzed. The results show that: The second aquifer in Anxin coalfield has a high confined water head, and the second aquifer of Anxin coalfield has a high confined water head in Heihe River Valley. With the exploitation of the mine and surrounding mines, it has a certain drainage effect on the groundwater, and its water head has a certain attenuation. The sandstone composite confined aquifer on the top of the No.4 coal roof has a larger head value, but the water richness of the composite aquifer is significantly different in both plane and vertical directions, and the recharge conditions and water richness are poor.The No.4 coal roof sandstone composite confined aquifer has little effect on the mining in Daliu coal mine, but there is a hidden danger of water inrush to the No.4 coal in Xinbai coal mine. Through the global sensitivity analysis, it is concluded that the total sensitivity of the model is small, and the results are relatively stable, which verifies the accuracy of the model.