Abstract: Aiming at the problem of drilling hole layout for gas extraction under the influence of mining in adjacent layer in high gas mine,introduced the theory of pressure relief effect and gas overflow during mining in outburst coal seam protective seam,the gas overflow effect of mining pressure relief in adjacent layer and the gas drainage effect of mining pressure relief in adjacent layer were demonstrated in fully mechanized caving face I011501,and the optimum layout scheme of pre-pumped boreholes was put forward. Through engineering practice and effect evaluation,the results showed that:Pre-extraction effect of I011501 fully mechanized caving face before mining still meets the requirements of relevant regulations under the condition of enlarging the distance between drilling holes and reducing the quantity of drilling construction works,6.9m gas drainage radius can meet the needs of gas drainage of fully mechanized caving face in M15.