For coal mines with thin bedrock and thick loose layers as the background, the occurrence of water and sand inrush disasters generally presents the characteristics of sudden and frequent occurrence. Such accidents are catastrophic and destructive. Production poses a great threat. Therefore, the key to preventing the occurrence of water and sand inrush disasters is to carry out advanced prediction, early warning and prevention work for such disasters. The multi-source information zoning evaluation method and the advanced production layout optimization technology provide a basis for the prevention and control of mine water and sand inrush disasters.