Abstract: In order to explore the effect of precise design and fine blast working process on loose blasting of rock mass in open-pit coal mine, this paper put forward several technical methods, including using air-deck charge structure and high density coefficient blasting technique, controlling the length of filling and charging, air-water coupling on handling holes with shoal water, which aim to solve the problems of soft-hard interbedded rock mass with horizontal bedding, unevenness of the bench surface and water-contained holes. Results of field tests indicate these methods can both improve blasting effect and reduce the cost of loose blasting.