Abstract: The key to open-pit coal mining is the setting up of water-resisting coal (rock) pillar and the control of slope stability, based on the background of the No. 2 Mine in Dananhu, Xinjiang, the paper studies the technique of coal (rock) pillar structure of the burnt rock slope under the coupling action of ground water and blasting vibration. Based on the field blasting test and numerical simulation analysis, the variation law of rock mass stress and Factor of safety is revealed, the range of blasting vibration is determined, and the water-proof coal (rock) pillar model of multi-rock strata is established, based on the analysis of the slope stability, the design scheme of the parameters of the burnt rock slope is given, and the parameters of the slope are optimized by the limit equilibrium method. The results show that the size of water-proof coal (rock) pillar is 50m at the boundary of burning area + 400m and the Slope Angle is 24 ° , which is 2 ° higher than the original design, under the coupling action of ground water and blasting vibration, the construction technology of water-resisting coal (Rock) pillar in burnt rock open-pit slope solves the problems of slope stability control and water gushing, under the premise of ensuring the safety of the slope, the maximum economic benefit of the burnt rock opencast mine is realized.