Aiming at the problems of deformation and failure of surrounding rock and difficult support of semi-coal rock roadway along goaf in gently inclined coal seam in deep high ground stress environment. The deformation mechanism of surrounding rock of gob-side entry in semi-coal rock is discussed by means of theoretical analysis, numerical simulation and field test. The evolution characteristics of stress and displacement of surrounding rock under different support conditions are analyzed, and the field engineering practice is carried out. The results show that the bearing capacity of small coal pillar is the key to control the deformation of surrounding rock. The deformation of surrounding rock o n both sides of roadway under the original bolt and cable support is asymmetric. The coal seams on both sides are easy to slide and bulge along the weak surface of coal rock. The bearing capacity of small coal pillar is insufficient due to shear failure. As the key part of support, the internal stress of small coal pillar is increased by 45% and the deformation of surrounding rock is greatly reduced after support optimization and grouting modification and reinforcement of surrounding rock. The excessive stress difference between the two sides under the influence of mining is the main reason for the asymmetric deformation of roadway surrounding rock. Grouting modification and reinforcement can restore the strength of surrounding rock and improve the stress environment. Based on this, the surrounding rock control scheme of " high-strength prestressed anchor cable combined with grouting modification and reinforcement " is proposed. The field practice shows that the surrounding rock control effect of the roadway in the test section is remarkable. The research results can provide reference for the surrounding rock control of deep semi-coal rock gob-side roadway under similar geological conditions.