Abstract: In view of the large amount of deep laneway deformation and support difficulties affected by multiple mining, the research object of Zhaozhuang Coal Mine 33092 Lane, through on-site research, theoretical analysis, numerical simulation and other ways to analyze the deformation and destruction pattern of deep coal lane surrounding rock affected by repeated mining, obtained the characteristics of deep lane surrounding rock bias stress distribution and the evolution law of plastic area. The results show that the "8" type distribution of the bias stress S1 and plastic area of 33092 lane-surrounding rock are skewed, which belongs to the obvious asymmetric destruction, and the form of on-site roadway destruction is basically the same as the theoretical analysis and numerical simulation results Based on the asymmetric distribution pattern of bias stress and plastic area, the asymmetrical support improvement scheme of 33092 lane is proposed and the industrial test is put into practice immediately, and the test results reveal that the scheme can maintain the stability of the roadway surrounding rock and ensure the safe use of the roadway during the service period.