Abstract: In order to explore the influence of different combinations of parameters (turning angle, blade pitch and airflow velocity) on the mist removal efficiency and pressure loss of the streamlined mist eliminators used in the mining wet dust removal fan, the three-dimensional numerical simulation of the flow of the air containing droplets in the streamlined demister was carried out by using FLUENT software. By introducing evaluation parameters to optimize structural parameters, a demister structure with high mist removal efficiency and low power consumption of dust removal fan is obtained. The results show that: with the decrease of the turning angle of the demister and the blade pitch, the mist removal efficiency and the pressure loss show an increasing trend. When the droplet size is greater than 10 μm. the mist removal efficiency increases with the increase of airflow velocity; When the droplet size is less than 10 μm, the mist removal efficiency decreases with the increase of airflow velocity. When the blade pitch is reduced from 40 mm to 20 mm, the pressure loss increases by only about 15%; However, when the speed increases from 2m/s to 6m/s, the pressure loss increases by about 5 times. Therefore, the influence of blade pitch on pressure loss is significantly lower than that of velocity. When the mist eliminator has the same mist removal efficiency, the mist eliminator with the parameters θ=90° and B=20 mm has the best performance. At this time, the evaluation parameters of the demister remain low, which can reduce the power consumption of the dust removal fan. The evaluation parameter relates the power consumption of the dust removal fan to the structural design of the mist eliminator, and provide an idea for the multi-parameter combination optimization design of the mist eliminator.