Abstract: In order to study the disaster-causing mechanism of rock burst in wide coal pillar gob-side entry with thick and hard roof, taking the 4104 working face of a mine in Binchang mining area as the engineering background, theoretical analysis, numerical simulation, field monitoring and other methods were used to study and analyze the vertical stress distribution of wide coal pillar and the law of overlying rock activity under two mining disturbances, and the evolution mechanism of dynamic and static loads and the disaster-causing mechanism of rock burst in the working face were obtained. Aiming at 44.5 m wide coal pillar and 20 m thick and hard sandstone strata above the roof, a dynamic and static load source separation control scheme based on blasting pressure relief of side coal body and presplitting pressure relief of deep hole blasting of roof is designed. Through the analysis of microseismic monitoring results, the surrounding rock activity of the roadway before the adjustment is reduced by 92%, and the control effect is significant.