In order to explore the prevention and control technology of rockburst in deep buried composite coal pillar working face, taking the 21201 working face of Hulusu Coal Mine as the engineering background, the distribution of the stress state before and after the formation of the composite coal pillar working face was studied, and the combined measures were proposed, and the effect was tested based on the change law of microseismic events before and after the combined pressure relief and erosion prevention measures. According to the analysis results, technical measures for joint pressure relief are designed. Affected by the superposition of the advance abutment pressure of the mining face and the lateral abutment pressure of the adjacent goaf, the composite coal pillar area will not only cause high stress concentration, but also easy to produce a large amount of energy accumulation. After the combined pressure relief, the daily average frequency and daily average energy of microseismic events have decreased by 71.7% and 75.6% respectively. The microseismic events above 103~104J have been significantly reduced and their spatial distribution is relatively scattered, which indicates that the combined pressure relief measures taken have significant effect and can effectively reduce the risk of impact.