In view of the technical problem that asymmetric large deformation of mining roadway under the influence of fault and mining disturbance, this paper takes the return air channel of Qipanjing I030902 as the research background, uses the methods of theoretical analysis, numerical simulation and field test to study the stress characteristics, displacement and plastic zone expansion law of roadway surrounding rock under different fault pillar widths, and analyzes the mechanism of asymmetric large deformation of surrounding rock of mining roadway near fault, The results show that the main causes of asymmetric deformation of roadway are abnormal stress in fault fracture zone, low rock mass strength and poor uniform bearing effect of support system. Combined with the deformation characteristics of surrounding rock and numerical simulation inversion results, a combined support technology of "full anchor cable+grouting reinforcement" is proposed. The monitoring results show that within 60 days after the repair, the maximum convergence of the two sides of the return air passage is 182 mm, and the maximum displacement of the top and floor is 176 mm. During the mining process of the working face, the maximum deformation of the two sides of station 1 # is 463mm, and the maximum displacement of the top and bottom plates is 485mm. This scheme can effectively improve the stress environment of the surrounding rock of the roadway in the fault area, reduce the development of the surrounding rock plastic zone, and ensure the normal use of the mining roadway.