Aiming at the technical difficulties of gas extraction in the thick seam with high gas content of Sima Coal Industry Co., Ltd., this paper discusses the gas extraction effect under different drilling arrangement modes, analyzes the influence of drilling parameters on crack expansion, and puts forward key technical parameters such as reasonable drilling arrangement mode, drilling spacing, drilling radius and effective time of gas extraction suitable for the thick seam of Sima Coal Industry Co., Ltd. On this basis, combined with the geological conditions of gas occurrence in No. 3 Coal Seam, the layout pattern of gas extraction boreholes in thick coal seams was designed. The mining roadway in 1207 working face is divided into three gas extraction sections, and the drilling layout mode combining "five hole layout" and "three hole layout" is implemented. The number of boreholes is reduced by about 30%, the extraction time of the first section of the working face is shortened to 110 days, and the gas extraction efficiency is increased by 70%, which greatly alleviates the time tension in the process of mining and mining face extraction connection.